The 2022 Nobel Prize in chemistry was awarded to scientists Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for their development of click chemistry and bioorthogonal chemistry. These ...
Bioorthogonal chemistry has revolutionised our ability to see the invisible by capturing the fleeting molecular events that sustain life. From single-molecule tracking to whole-organism imaging, ...
Coined by 2022 Nobel laureate Carolyn Bertozzi, bioorthogonal chemistry encompasses a class of click reactions that are both fast and biologically inert, making them particularly useful in precision ...
On Oct. 4, the 2022 Nobel Prize in Chemistry was awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for their work in the development of click chemistry and bioorthogonal chemistry, ...
Covalent chemical probes – chemical probes that form a covalent bond with their target biomacromolecule(s) represent powerful tools that can be used for biology discovery, target validation (or ...
Chemists looking to develop new techniques in bioorthogonal chemistry can encounter a kind of paradox. Stable, biocompatible molecules are required for use in living tissues. But the reactants must ...
In this bonus episode of C&EN’s Bonding Time, we hear from 2022 chemistry Nobel laureates Carolyn Bertozzi and K. Barry Sharpless, who shared the prize along with Morten Meldal for their work on click ...
Winners of the 2022 Nobel Prize in chemistry. From left to right, Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless. © Nobel Prize Outreach. Illustration by ...