A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

Different variants of a gene, known as isoforms, can be transcribed and translated at varying levels within a cell or tissue. These isoforms are commonly a result of alternative splicing, which ...

A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...