One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...
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New 4D genome maps reveal how genes fold, interact, and reposition as cells divide
New 3D genome maps reveal how DNA folding controls gene activity, offering fresh clues into disease and cell function.
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA's shape have an important influence on gene activity and energy production.
Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, ...
Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...
The researchers found that, contrary to how it’s depicted in most textbooks, chromatin does not fold in on itself in an organized manner to create distinct structures. Instead, it forms a pliable, ...
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