LONDON, England—In ACS patients receiving PCI, bivalirudin reduces major bleeding and mortality but not net adverse clinical events (NACE) vs heparin, according to results presented September 1, 2015, ...

Heparin (ball and stick structure) activates antithrombin-III (gray) to bind to and inhibit thrombin (purple). All this raises the questions: Just what is heparin? Where does it come from? What does ...

Patients with ST-segment elevation myocardial infarction (STEMI) who receive early emergency heparin can be safely switched to bivalirudin before undergoing percutaneous coronary intervention (PCI).

July 7, 2004 -- Enoxaparin is noninferior to unfractionated heparin for the treatment of acute coronary syndromes (ACS), according to the results of two large studies published in the July 7 issue of ...

Unfractionated heparin (UFH) serves as a commonly used anticoagulant. It is widely utilized for a variety of reasons, including to 1) anticoagulate patients and help treat and / or prevent thrombosis, ...

October 14, 2008 (Turin, Italy) — Low-risk patients with uncomplicated lesions can have elective PCI safely performed using dual antiplatelet therapy without systemic anticoagulation, the so-called ...

Correctly diagnosing heparin resistance in patients on extracorporeal membrane oxygenation (ECMO) is challenging. In patients with sepsis, the differential diagnosis for heparin resistance is large, ...

Unfractionated heparin is often used as adjunctive therapy with fibrinolysis in patients with ST-elevation myocardial infarction. We compared a low-molecular-weight heparin, enoxaparin, with ...

The Case: A previously healthy 24-year-old man presented to the emergency department with sudden onset of severe periumbilical and right costovertebral pain accompanied by nausea and vomiting. His ...

Healthy newborn infants rarely Buffer from thrombosis, despite their low plasma antithrombin III (ATIII) levels. In adults, ATIII is the main inhibitor of thrombin; α 2-macroglobulin (α 2 M) and ...

We read with concern the analysis by Davidson et al. (Sept. 26 issue). 1 They use the pooled placebo groups from two sepsis trials, divided into two groups — patients who either were receiving heparin ...

Heparins are a group of related compounds comprised of a mixture of glycosaminoglycans usually derived from porcine intestine. They exert their effect by binding to antithrombin, which inhibits both ...