Adrenomedullin, a hormone first identified in an adrenal medullary tumor, disrupts the effect of insulin on the endothelium of blood vessels, leading to insulin resistance linked to obesity and type 2 ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...

This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites ...

Integrated metabolomic, genetic, and lifestyle data improved type 2 diabetes risk prediction and highlighted new targets for ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Insulin resistance, or low insulin sensitivity, happens when cells throughout the body don’t respond properly to the hormone insulin, especially cells in: Insulin is a pancreatic hormone that allows ...

Researchers at the University of Oxford have discovered that the most common liver disease follows a strong day-night pattern ...