The intestinal phenotype of cystic fibrosis (CF) transmembrane conductance regulator deficient mice includes altered cell homeostasis and a distended crypt-villus axis, which, in previous work, was ...

A new study suggests that stem cells are able to integrate cues from their surroundings and coordinate their behavior across tissue through networks of vasculature in their close vicinity. To act as a ...

In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut regeneration and long-term stability. Their findings may have ...

The human small intestine is an essential organ that helps us absorb nutrients and vitamins from food. It is an average of 6 meters long and is covered with millions of villi that are separated by ...

Researchers at the University of Gothenburg have now shown how mucus protects the small intestine in mice. In the future, this finding may lead to new ways of preventing relapse in Crohn’s disease in ...

Researchers at Baylor College of Medicine have uncovered a more detailed picture of how the intestinal epithelium – the lining of the intestines – heals itself after infection with rotavirus. A ...

Stem cells are a hot topic for creating medical treatments. However, scientists still do not fully understand how they choose to divide or differentiate to renew organs. Researchers have now found a ...

To act as a robust barrier against pathogens while also absorbing needed nutrients, the lining of the intestines must regenerate on a daily basis to remain equal to the task. The intestine’s resident ...