Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

Angiopoietin-like protein 3 (ANGPTL3) inhibits lipoprotein and endothelial lipases. ANGPTL3 loss-of-function genetic variants are associated with decreased levels of low-density lipoprotein ...

Korean researchers have developed a gene therapy method that accurately corrects the representative mutation (c.220C>T) of the MPZL2 gene that causes hereditary hearing loss, and succeeded in proving ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

Dominika Pilat, PhD, and Ana Griciuc, PhD, of the Department of Neurology at Massachusetts General Hospital are the lead and senior authors of a paper published in Neuron, "The Gain-of-Function ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...