Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...
Figure 3. ACE inhibitors and ARBs have different sites of action within the RAS pathway. The solid arrows indicate activation, and the dashed arrows indicate inhibition. ACE = angiotensin-converting ...