Deafness, the most common sensorineural hearing loss at all stages of life, occurs either independently or as part of ...

It is suggested to submit at least 2 anatomically distinct tumors, however a single tumor can be provided. If a blood specimen is provided with the submitted tumor, confirmatory testing in the ...

Patients with classic NF1 including the presence of cutaneous neurofibromas or Lisch nodules, as no genetic heterogeneity demonstrated so far associated with this phenotype. The NF1-only by NGS ...

Limitations in DNA sequencing technology make it difficult to detect some major mutations often linked to cancer, such as the loss or duplication of parts of chromosomes. Now, methods developed by ...

FMS-like tyrosine kinase 3 (FLT3) is mutated in approximately one third of acute myeloid leukemia cases. The most common FLT3 mutations in acute myeloid leukemia are internal tandem duplication (ITD) ...

Leading cancer expert solve long-standing question of how various types of mutations in just one gene cause different types of diseases. Leading cancer experts at the University of Birmingham have ...

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes. These mutations are found in nearly 100 per ...

Bottom line: A new mutation was identified in 9 percent of relapsed cases of pediatric acute myeloid leukemia (AML) that may define a new subtype of the disease. While the researchers identified the ...